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PLASMA RENIN ACTIVITY; PRA

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PLASMA RENIN ACTIVITY; PRA

Renin is a proteolytic enzyme released from juxtaglomerular cells of the kidney. The enzyme cleaves a substrate to produce Angiotensin I which in turn produces Angiotensin II. This metabolite plays a key role in various forms of hypertension. Increased levels are seen in Renal hypertension, Addison’s disease and Secondary hypoaldosteronism. Low levels are detected in Hyporeninemic hypoaldosteronism and Primary aldosteronism

Pre-test Information : Overnight fasting is preferred. Patient should be ambulatory or upright 2 hours prior to the test. No medication 3 weeks prior to draw is recommended

Report Delivery : Same day

PLASMA RENIN ACTIVITY; PRA

Test Code P-18
Test Description **PLASMA RENIN ACTIVITY; PRA
Clinical Category KIDNEY DISORDERS
Sample 3 mL (2.5 mL min.) plasma IN EDTA tube. Collect blood between 8 am to 10 am. Patient should be ambulatory / upright 2 hours prior to the test. Overnight fasting is preferred
Method/Technology CLIA
Storage/Temp
Reporting Time DAILY